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ULTRASTRUCTURAL CHANGES OF THYROTROPIC CELLS IN THE DYNAMICS OF EXPERIMENTAL IMMUNOSTIMULATION

CBU International Conference on Innovation in Science and Education

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Title ULTRASTRUCTURAL CHANGES OF THYROTROPIC CELLS IN THE DYNAMICS OF EXPERIMENTAL IMMUNOSTIMULATION
 
Creator Bobrysheva, Inessa
Kashchenko, Svetlana
 
Description The endocrine and immune systems are interrelated via a bidirectional network.Thyroid-stimulating hormone plays a critical role as an endogenous mediator of immune activity. Purpose of study was to determine the dynamics of changes of thyrotropic cells ultrastructure in modeling immunostimulation in mature male rats by subcutaneous injection of imunofan in a dosage 0,7 mg/kg of body weight.The pituitary samples were taken on 1st, 7th, 15th, 30th and 60th, day after treatment and thenfixed in glutaraldehyde for electron microscope. The study showed theincrease of functional activity of the thyrotropic cells. The significant increase of areas of the cells and their nuclei, area of mitochondria and secretory granules was established since 7th day after imunofan treatment.
 
Publisher Central Bohemia University, o.p.s.
 
Contributor —
 
Date 2013-06-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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Format application/pdf
 
Identifier http://ojs.journals.cz/index.php/CBUConference2013/article/view/47
10.12955/cbup.2013.47
 
Source CBU International Conference Proceedings; Vol 1 (2013): CBU International Conference Proceedings 2013; pp. 291-295
1805-9961
1805-997X
 
Language eng
 
Relation http://ojs.journals.cz/index.php/CBUConference2013/article/view/47/51
 
Rights Copyright (c) 2013 Inessa Bobrysheva, Svetlana Kashchenko
https://creativecommons.org/licenses/by/3.0/