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I farmaci per lo scompenso cardiaco: criteri di scelta razionale e costo-efficace

Farmeconomia

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Title I farmaci per lo scompenso cardiaco: criteri di scelta razionale e costo-efficace
 
Creator Costa, Francesco Vittorio
Pradelli, Lorenzo
 
Subject Pharmacoeconomics; Health economics
Chronic heart failure (CHF); ACE-inhibitors; Beta-blockers; Generic drugs
 
Description Chronic heart failure (CHF) is the final phase of many common cardiovascular diseases. Consequently, it represents a frequent clinical condition: it’s estimated that in developed countries, Italy included, its prevalence exceeds 3%. CHF is also burdensome from an economical point of view, as it absorbs more than 2% of the Italian total health care budget. The main cost driver in CHF, accounting for approximately two thirds of its total expense, is represented by hospital admissions for relapse. The most frequent reason for relapse, in turn, is inadequate treatment, intended both as low patient compliance to prescribed drug regimens and as inappropriate prescribing. Evidence-based guidelines for the optimal pharmacological treatment of CHF have been developed and are constantly updated, and it’s demonstrated that the stricter the adherence to these recommendations, the better the clinical and economic outcomes. Pharmacoeconomic studies conducted on the use of ACE-inhibitors and beta-blockers, in particular, have shown that correct therapeutic strategies can be cost-saving in CHF management, besides providing important clinical benefits. The expansion of generic drug market has brought by a reduction in pharmaceutical prices, allowing to offer the benefits of these highly effective, and cost-effective, treatments for CHF to a larger number of patients, without increasing the global pharmaceutical expense, but probably reducing the total economical burden of the disease.
 
Publisher SEEd Medical Publishers
 
Date 2005-09-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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Format application/pdf
 
Identifier https://journals.edizioniseed.it/index.php/FE/article/view/836
10.7175/fe.v6i3.836
 
Source Farmeconomia. Health economics and therapeutic pathways; Vol 6, No 3 (2005); 215-226
2240-256X
 
Language eng
 
Relation https://journals.edizioniseed.it/index.php/FE/article/view/836/920
 
Rights Copyright (c) 2005 Farmeconomia. Health economics and therapeutic pathways
http://creativecommons.org/licenses/by-nc/4.0