Since 2014
Prophylaxis against febrile neutropenia with pegfilgrastim in Italy: a budget impact analysis
Farmeconomia
View Archive Info| Field | Value | |
| Title |
Prophylaxis against febrile neutropenia with pegfilgrastim in Italy: a budget impact analysis
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| Creator |
Rosti, Giovanni
Lebboroni, Maria Cerchiari, Ario Katz, Pablo |
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| Subject |
Pharmacoeconomics; Health economics
Pegfilgrastim; Neutropenia febbrile; Budget impact |
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| Description |
Introduction: prophylaxis with granulocyte colony-stimulating factors (G-CSF) is indicated for reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy.
Objective: to evaluate the budgetary impact for the Italian NHS.
Design: a decision-analytic model has been developed to analyze the budget impact from the national health care system perspective. Costs include direct healthcare costs to the public payer of G-CSFs as well as their administration costs and costs of FN-related events. The comparison has been done using prophylaxis with G‑CSF (filgrastim for 11 days, pegfilgrastim, lenograstim for 11 days) and antibiotics.
Patients and participants: The population of interest for the analysis were patients with breast cancer in stage II and III and patients with non-Hodgkin’s lymphoma (NHL).
Main outcome measures and results: for all the three patients group (NHL, Breast II and III), and for all the chemotherapy regimens (CHOP 21 and R-CHOP 21 for NHL, AC-T, TAC and TC for Breast stage II and III) the budget impact analyses shows a cost reduction for the Italian NHS, as a result of an increase of the use of pegfilgrastim.
Conclusions: in Italy, a treatment strategy including pegfilgrastim as either primary or secondary prophylaxis provides value for money.
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| Publisher |
SEEd Medical Publishers
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| Contributor |
—
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| Date |
2011-09-15
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — |
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| Format |
text/html
application/pdf |
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| Identifier |
https://journals.edizioniseed.it/index.php/FE/article/view/126
10.7175/fe.v12i3.126 |
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| Source |
Farmeconomia. Health economics and therapeutic pathways; Vol 12, No 3 (2011); 119-127
2240-256X |
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| Language |
eng
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| Relation |
https://journals.edizioniseed.it/index.php/FE/article/view/126/128
https://journals.edizioniseed.it/index.php/FE/article/view/126/131 |
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| Coverage |
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| Rights |
Copyright (c) 2011 Farmeconomia. Health economics and therapeutic pathways
http://creativecommons.org/licenses/by-nc/4.0 |
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