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Simulating the development and progression of Chronic Kidney Disease and osteoporosis in people living with HIV

Farmeconomia

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Title Simulating the development and progression of Chronic Kidney Disease and osteoporosis in people living with HIV
 
Creator Adami, Silvano
Maggi, Paolo
Montinaro, Vincenzo
Povero, Massimiliano
Pradelli, Lorenzo
Bellagamba, Rita
Bonfanti, Paolo
Di Biagio, Antonio
Rusconi, Stefano
Di Campli, Francesco Maria
Forastieri, Giuseppe
Mancini, Michele
 
Subject —
HIV; Chronic Kidney Disease; Osteoporosis
 
Description The “chronicization” of HIV infection brings about a growing necessity to attentively evaluate current and potential complications when prescribing the individual therapeutic regimen. Starting from this need, we developed two HIV-comorbidity simulators that, basing on the evidence available in medical literature and starting from the current clinical and demographic features of the individual patient, project and compare the risks of developing and worsening of nephropathy and osteopathy associated with possible ARV regimens. These simulators are embedded in a desktop, user-friendly software thought to be used by the treating physician during prescription discussion with his/her patients, in order to highlight expected clinical outcomes and healthcare resource consumption that may differ according to the therapeutic strategy selected. In this article we present the sources and methods used in developing the mathematical models, alongside a set of examples and the results of cohort-level validation runs.
 
Publisher SEEd Medical Publishers
 
Contributor —
 
Date 2016-02-29
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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Format text/html
application/pdf
 
Identifier https://journals.edizioniseed.it/index.php/FE/article/view/1236
10.7175/fe.v17i1S.1236
 
Source Farmeconomia. Health economics and therapeutic pathways; Vol 17, No 1S (2016); 3-23
2240-256X
1721-6915
 
Language eng
 
Relation https://journals.edizioniseed.it/index.php/FE/article/view/1236/1502
https://journals.edizioniseed.it/index.php/FE/article/view/1236/1503
 
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Rights Copyright (c) 2016 Farmeconomia. Health economics and therapeutic pathways
http://creativecommons.org/licenses/by-nc/4.0