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Economic and clinical value of levofloxacin

Farmeconomia

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Field Value
 
Title Economic and clinical value of levofloxacin
 
Creator Eandi, Mario
Zaniolo, Orietta
 
Subject Pharmacoeconomics; Health economics
Levofloxacin; Community-acquired pneumonia (CAP); Complicated urinary tract infections (cUTI); Acute exacerbation of chronic bronchitis (AECB); Skin and soft tissue infection (SSTI)
 
Description Levofloxacin is a newer fluoroquinolone, with broad spectrum of antibacterial activity and good tolerability. This drug has a pharmacokinetic and pharmacodynamic profile that allows a once-a-day administration and offers the potential for intravenous-to-oral switch therapy. Due to these characteristics, the principal guidelines recommend it, as an option for the empirical therapy of patients with mild or more severe community acquired pneumonia (CAP), acute exacerbation of chronic bronchitis (AECB), complicated urinary tract infection (cUTI) and skin and soft tissue infection (SSTI). These pathologies are common causes of morbidity and mortality and place a large burden on medical and economic resources, specially if hospitalization is required. The implementation of a critical pathway, based on levofloxacin use and on a risk prediction rule to establish the need for hospitalization, has the potential to decrease healthcare resource consumption without impairment of clinical outcomes, with respect to conventional management. The possibility of switch therapy allows to reduce length of hospital stay, with a saving in both direct and indirect costs, and an increase in patient satisfaction. In summary, when used according to appropriateness criteria and for approved indications, levofloxacin offers favorable economic features for the healthcare provider, whilst guaranteeing a positive impact on patient functioning and quality of life.
 
Publisher SEEd Medical Publishers
 
Contributor
 
Date 2006-01-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://journals.edizioniseed.it/index.php/FE/article/view/257
10.7175/fe.v7i4.257
 
Source Farmeconomia. Health economics and therapeutic pathways; Vol 7, No 4 (2006); 223-237
2240-256X
1721-6915
 
Language eng
 
Relation https://journals.edizioniseed.it/index.php/FE/article/view/257/239
 
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Rights Copyright (c) 2006 Farmeconomia. Health economics and therapeutic pathways
http://creativecommons.org/licenses/by-nc/4.0