Record Details

Cost-effectiveness of intravitreal therapy in Age-Related Macular Degeneration

Farmeconomia

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Field Value
 
Title Cost-effectiveness of intravitreal therapy in Age-Related Macular Degeneration
 
Creator Neri, Piergiorgio
Arapi, Ilir
Eandi, Chiara Maria
Pirani, Vittorio
Mariotti, Cesare
Giovannini, Alfonso
 
Subject
Age-Related Macular Degeneration; Anti-VEGF; Intravitreal injection
 
Description Age-related macular degeneration (AMD) is still referred to as the leading cause of severe and irreversible visual loss world-wide. Advances in medical research have identified vascular endothelial growth factor (VEGF) as an important pathophysiological player in neovascular AMD and intraocular inhibition of VEGF as one of the most efficient therapies. Anti-VEGFs currently used to treat AMD included a monoclonal antibody (bevacizumab), an antibody fragments (ranibizumab), a fusion protein (aflibercept), and an aptamer (pegaptanib). The wide introduction of anti-VEGF therapy has led to an improvement in the prognosis of patients affected by AMD, with a consequent effects on the burden of care due to highly priced drugs, increasing patient numbers, and long-term disease chronicity. Aim of this review is to present an overview of available therapeutic strategies in AMD in term of clinical efficacy and economic sustainability.
 
Publisher SEEd Medical Publishers
 
Contributor
 
Date 2014-12-23
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format text/html
application/pdf
 
Identifier http://journals.edizioniseed.it/index.php/FE/article/view/976
10.7175/fe.v15i4.976
 
Source Farmeconomia. Health economics and therapeutic pathways; Vol 15, No 4 (2014); 129-138
2240-256X
1721-6915
 
Language eng
 
Relation http://journals.edizioniseed.it/index.php/FE/article/view/976/1188
http://journals.edizioniseed.it/index.php/FE/article/view/976/1189
 
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http://creativecommons.org/licenses/by-nc/4.0