Record Details

Ankylosing spondylitis and psoriatic arthritis: clinical and economic consequences of the use of etanercept

Farmeconomia

View Archive Info
 
 
Field Value
 
Title Ankylosing spondylitis and psoriatic arthritis: clinical and economic consequences of the use of etanercept
 
Creator Sacchi, Viola
Zaniolo, Orietta
Olivieri, Ignazio
 
Subject Pharmacoeconomics; Health economics
Psoriatic arthritis; Ankylosing spondylitis; Etanercept
 
Description Spondyloarthritis (SpA) is the name for a family of inflammatory rheumatic disease that can affect the spine and joints, ligaments and tendons. Spondyloarthritis disease include ankylosing spondylitis, reactive arthritis, psoriatic arthritis, the spondylitis associated with the inflammatory bowel diseases and the undifferentiated spondyloarthritis. The most common treatments prescribed for spondyloarthritis are nonsteroidal anti-inflammatory drugs (NSAIDs) given in combination with disease-modifying antirheumatic drugs (DMARDs). Due to a recently suggested role of the tumour necrosis factor (TNFa) in the pathogenesis of SpA, new therapies specifically blocking TNFa have been investigated. Anti-TNF medications currently available on the Italian market are etanercept, infliximab and adalimumab. The aim of the present work was to furnish a clinical and pharmaco-economical profile of etanercept in treatment of psoriatic arthritis and ankylosing spondylitis based on a review of the published literature. Economical evaluations performed in several countries indicate that total treatment costs are lower with etanercept and adalimumab as compared to infliximab, mainly because of differences in the route of administration. Etanercept appears to be cost effective for the treatment of psoriatic arthritis and ankylosing spondylitis especially considering improved health related quality of life and lower medical costs due to superior efficacy of treatment.
 
Publisher SEEd Medical Publishers
 
Contributor
 
Date 2010-06-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://journals.edizioniseed.it/index.php/FE/article/view/184
10.7175/fe.v11i2.184
 
Source Farmeconomia. Health economics and therapeutic pathways; Vol 11, No 2 (2010); 63-76
2240-256X
1721-6915
 
Language eng
 
Relation https://journals.edizioniseed.it/index.php/FE/article/view/184/167
 
Coverage


 
Rights Copyright (c) 2010 Farmeconomia. Health economics and therapeutic pathways
http://creativecommons.org/licenses/by-nc/4.0